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Paper: DRP-1-dependent autophagy, heat stress and mitochondrial rebuilding

Autophagy facilitates mitochondrial rebuilding after acute heat stress via a DRP-1–dependent process Yanfang Chen, Romane Leboutet, Céline Largeau, Siham Zentout, Christophe Lefebvre, Agnès Delahodde, Emmanuel Culetto, Renaud Legouis.J Cell Biol. 2021 Apr 5;220(4):e201909139. doi: 10.1083/jcb.201909139. Pubmed PMID: 33734301. Contact: renaud.legouis@i2bc.paris-saclay.fr Lien vers l’article/Link to the paper: https://rupress.org/jcb/article-abstract/220/4/e201909139/211895/Autophagy-facilitates-mitochondrial-rebuilding?redirectedFrom=fulltext Résumé de l’article: Un processus d’autophagie dépendant de…

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Team: Signaling and pathophysiology of heart failure and aging – April 2021

Team: Signaling and pathophysiology of heart failure and aging Team presentation Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), INSERM UMR1297, CHU Rangueil, 1 avenue du Pr Jean Poulhès, 31000 Toulouse, France website : www.i2mc.inserm.fr Team Leaders : Frank Lezoualc’h, DR INSERM, frank.lezoualch@inserm.fr Jeanne Mialet-Perez, CRCN INSERM, jeanne.perez@inserm.fr Team members : Caroline Conte, MCU Yannis Sainte-Marie,…

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Paper: BAG6, a new receptor for mitophagy?

BAG6 promotes PINK1 signaling pathway and is essential for mitophagy Romain Ragimbeau, Leila El Kebriti, Salwa Sebti, Elise Fourgous, Abdelhay Boulahtouf, Giuseppe Arena, Lucile Espert, Andrei Turtoi, Céline Gongora, Nadine Houédé, Sophie Pattingre. FASEB J. 2021 Feb;35(2):e21361. doi: 10.1096/fj.202000930R. Pubmed PMID: 33522017. Contact: sophie.pattingre@inserm.fr Lien vers l’article / Link to the paper: https://faseb-onlinelibrary-wiley-com.proxy.insermbiblio.inist.fr/doi/10.1096/fj.202000930R Résumé de…

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Paper: ER-phagy, VAMP7-Dependent Secretion of RTN3 and Neurite Growth

Role of VAMP7-Dependent Secretion of Reticulon 3 in Neurite Growth José Wojnacki, Sébastien Nola, Philippe Bun, Béatrice Cholley, Francesca Filippini, Mary T. Pressé, Joanna Lipecka, Sin Man Lam, Julie N’guyen, Axelle Simon, Amine Ouslimani, Guanghou Shui, Claudio Marcelo Fader, Maria Isabel Colombo, Ida Chiara Guerrera and Thierry Galli. Cell Reports. DOI: 10.1016/j.celrep.2020.108536. Pubmed PMID: 33357422….

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Paper: Lysosomal degradation and chromosomal stability

Lysosomal degradation ensures accurate chromosomal segregation to prevent chromosomal instability Eugènia Almacellas, Joffrey Pelletier, Charles Day, Santiago Ambrosio, Albert Tauler, Caroline Mauvezin. Autophagy. DOI: 10.1080/15548627.2020.1764727. Pubmed PMID: 32573315. Contacts: Dr. Albert Tauler, tauler@ub.edu and Dr. Caroline Mauvezin caroline.mauvezin@gmail.com Lien vers l’article / Link to the paper: https://www.tandfonline.com/doi/full/10.1080/15548627.2020.1764727 Résumé de l’article: Une équipe du Laboratoire du…

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Paper: CMA and evolution: insight from fish

Chaperone-Mediated Autophagy in the Light of Evolution: Insight from Fish L Lescat, V Véron, B Mourot, S Péron, N Chenais, K Dias, N Riera, F Beaumatin, K Pinel, M Priault, S Panserat, B Salin, Y Guiguen, J Bobe, A Herpin, I Seiliez. Molecular Biology and Evolution. DOI: 10.1093/molbev/msaa127. Pubmed PMID: 32437540 Contacts: Iban Seiliez Lien…

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Paper Highlight: BHRF1, mitophagy & antiviral response

  BHRF1, a BCL2 viral homolog, disturbs mitochondrial dynamics and stimulates mitophagy to dampen type I IFN induction Vilmen G, Glon D, Siracusano G, Lussignol M, Shao Z, Hernandez E, Perdiz D, Quignon F, Mouna L, Poüs C, Gruffat H, Maréchal V, Esclatine A, Autophagy. 2020. doi: 110.1080/15548627.2020.1770979. PubMed PMID: 32401605 Contacts: Audrey Esclatine Lien…

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Paper Highlight: PI3K, stress and autophagy

PI3KC2α-dependent and VPS34-independent generation of PI3P controls primary cilium-mediated autophagy in response to shear stress Boukhalfa A, Nascimbeni AC, Ramel D, Dupont N, Hirsch E, Gayral S, Laffargue M, Codogno P, Morel E. Nat Commun. 2020 Jan 15;11(1):294. doi: 10.1038/s41467-019-14086-1. PubMed PMID: 31941925 Contacts: Muriel Laffargue, Patrice Codogno, Etienne Morel Lien vers l’article / Link…

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