Keystone Symposia : Selective autophagy (22-26/04/2018, Kyoto, Japan) CFATG
Keystone Symposia : Selective autophagy (22-26/04/2018, Kyoto, Japan)
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Keystone Symposia : Selective autophagy

Date: April 22—26, 2018
Location: Westin Miyako Kyoto, Kyoto, Japan

Meeting summary:

Autophagy is an evolutionarily conserved membrane trafficking process which delivers cargos from the cytoplasm to lysosomes and is critical for cellular homeostasis. Although autophagy has long been perceived as a non-selective pathway, researchers are increasingly realizing that autophagy can be highly selective. It has been shown that protein aggregates and damaged or superfluous organelles such as mitochondria, ER, peroxisomes, endosomes and lysosomes can be degraded by autophagy in a highly selective manner. Selective autophagy has also been shown to play an important role in controlling intracellular pathogens. Since several diseases have been linked to dysfunctional selective autophagy, researchers’ interest in the process is increasing. Altering the autophagy level has become a therapeutic target in various diseases, while the exact mechanisms of selective autophagy for each target remain to be uncovered. The primary goal of this program is to integrate and discuss the latest information about the underlying mechanisms of selective autophagy and its implication in diseases.

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