emc2020 – LSA.8: Imaging Self Eating – Autophagy under the Microscope
Date: August 23-28, 2020
Location: Copenhagen, Danemark
Abstract deadline: March 15, 2020
Eeva-Liisa Eskelinen and Nick Ktistakis are organizing a session on imaging in autophagy research in the European Microscopy Congress in Copenhagen in August 2020.
Session chairs: Eeva-Liisa Eskelinen and Nicholas Ktistakis
Invited speakers: Lucy Collinson, The Francis Crick Institute, UK, and Muriel Mari, University Medical Centre Groeningen, NL
Autophagy is a life-supporting catabolic process conserved from yeast to man. It was originally described using electron microscopy, soon after the first electron microscopes became available for researchers. Genes and proteins regulating autophagy were discovered in the 1990ies and these findings were awarded with a Nobel prize to Yoshinori Ohsumi in 2016. The knowledge on autophagy proteins has made it possible to image this process in live cells and to combine live cell imaging with other cutting-edge microscopy methods including super resolution, electron tomography and focused ion beam scanning electron microscopy. Imaging has brought autophagy field forward more than any other methodology, with the exception of yeast genetics that revealed the identity of autophagy genes. We aim to invite the world leaders on autophagy research to demonstrate how different types of imaging technologies are applied in their work. The approaches are likely to include live-cell imaging, super resolution, focused ion beam scanning electron microscopy, electron tomography and immuno electron microscopy.