H2020 Marie Sklodowska-Curie Innovative Training Networks (ITN) grant awarded to a consortium of 15 European groups and SMEs. The consortium includes 9 Transautophagy participants (Anaxomics, Patricia Boya, Patrice Codogno, Eeva-Liisa Eskelinen, Heinz Jungbluth, Claudine Kraft, Tassula Proikas-Cezanne, Fulvio Reggiori, Anne Simonsen) and will closely collaborate with Transautophagy through the reciprocal advertisement of activities.
The manipulation of autophagy has an enormous therapeutic potential to revolutionize the way we currently treat cancers, neurodegenerative disorders, inflammatory and infectious diseases. Despite the great promises made by pioneering medical studies, the still limited applied research on autophagy has hampered the translation of fundamental knowledge into clinical-grade products and improved healthcare. Applied autophagy research is essential to understand the roles of autophagy in the different physiological and pathological situations, to generate (disease) models and develop biomarkers and assays to assess its progress.
The goal of the ITN Driving next generation autophagy researchers towards translation (DRIVE) is to train young scientists to fill this gap. DRIVE will equip its ESRs with an unique combination of knowledge and experimental expertise that are brought together in this consortium by the different partners. The realization of their projects in applied autophagy research will benefit of an exceptional interdisciplinary platform integrating cell biology, biochemistry, molecular biology, genetics, chemistry and “omics” approaches. In addition, DRIVE ESRs will acquire competencies to exploit the results for the development of products and techniques of commercial value. These ESRs will also be trained in disseminating results and knowledge through modern channels of communication.
DRIVE will, therefore, create a new generation of autophagy researchers trained in both academic and industrial settings, with the skills required to accelerate the integration of fundamental knowledge into translation. They will also have increased career perspectives and will put Europe in the lead for the exploitation of autophagy therapy for the benefit of public healthcare.
COST/European Cooperation in Science and Technology : TRANSAUTOPHAGY
It is with an extreme pleasure that the CFATG extends its warmest congratulations to Professor Yoshinori Ohsumi for obtaining the Nobel Prize in Medicine and Physiology, in the context of its works on Autophagy.
Among his advances in the field of Autophagy, Pr Oshumi identified the first yeast mutant with defective autophagy in 1993, and in the mid-90s he identified the first genes involved in the process.
This award recognizes an exceptional researcher, but also all the work of those who contributed, who are contributing and who will contribute to the knowledge on Autophagy, from its most fundamental aspects to its implications in pathophysiology.
Find the Nobel Prize lecture and all the comments from leaders in the field: Here
Autophagy, which literally means « self-eating », is involved in the removal and recycling of cellular waste. Malfunction of autophagy has been linked to a wide range of human diseases, including Parkinson’s, Alzheimer’s, and Crohn’s diseases, cancers, myopathies, cardiovascular disorders, as well as autoimmune and infectious diseases.
CFATG has at heart to promote, to strengthen and to share the knowledge in the field of Autophagy.
B cell homeostasis and autoimmunity
Institut de Biologie Moléculaire et Cellulaire, Strasbourg
Team leader: Pr Pauline Soulas Sprauel
Publication Highlights: Autophagy articles published by french laboratories and selected by CFATG.
Elise Jacquin – Postdoctoral scientist
The Florey Lab, Signalling Department
The Babraham Institute, Cambridge, UK
“I have greatly benefited from the support of the CFATG during my postdoctorate and I warmly thank this vibrant network of researchers for allowing me to be part of this inspiring meeting which convinced me to carry on working on autophagy.”
Yinxing MA (Institut Gustave Roussy, Villejuif):
“I would like to warmly thank the French club of Autophagy (CFATG) for awarding me a travel grant in order to attend the “The 8-th International Symposium on Autophagy”. This conference took place in 29 May – 1 June 2017, Nara, Japan. Where I had the opportunity to present my work during several poster sessions. It was amazing and inspiring to learn current projects from autophagy leading scientist in the field”.
Coralie Daussy (CPBS, Montpellier) : “I would like to warmly thank the French club of Autophagy (CFATG) for awarding me a travel grant in order to attend the ”Gordon Research Seminar and Conference” on “Autophagy in stress, development and diseases”. This congress took place on March 2016, in Ventura, USA. I had the opportunity to present my work during a short talk and several poster sessions. It was a significant event for me and it has been truly inspiring”.
Fengjuan Wang (IBMC, Strasbourg) : “I was very honored to obtain a travel grant from CFATG which allowed me to attend and present in the 2016 Gordon Research Conference&Seminar on “Autophagy in Stress, Development and Disease” (California, United States), a great opportunity to interact with the world-leading autophagy experts, absorb the most updated knowledge in this field, and discover California. Last but not least, through CFATG events, I have established both professional contacts and friendship, from which I greatly benefit”.
Aurora Scrivo (Institute for Neurosciences, Montpellier): “I would like to greatly thank the CFATG to allow me to participate, thanks to the travel grant, to the “7th Proteasome & Autophagy workshop”, that took place in Clermont Ferrand (France) from 6 to 8 April 2016. It was for me a very exciting possibility to meet with several international experts, giving me the opportunity to establish solid contacts for my future post-doc.”